Bob Hoskins
Mario Mario

John Leguizamo
Luigi Mario

Dennis Hopper
King Koopa

Samantha Mathis
Daisy

Fisher Stevens
Iggy

Richard Edson
Spike

Fiona Shaw
Lena

Dana Kaminski
Daniella

Mojo Nixon
Toad

Gianni Russo
Scapelli

Francesca P. Roberts
Bertha

Lance Henriksen
The King

Sylvia Harman
Old Lady

Desiree Marie Velez
Angelica

Andrea Powell
Brooklyn Girl

Heather Pendergast
Brooklyn Girl

Melanie Salvatore
Brooklyn Girl

John Fifer
Goomba Toad

Don Lake
Sgt. Simon

Terry Finn
Hatcheck Girl

Thomas Merdis
Goomba

Michael Harding
Goomba

Michael Lynch
Goomba

Scott Mactavish
Goomba

Wallace Merck
Goomba

Mona B. Fierro
Nun

Karen Brigman
Nun

Christi K. Work
Nun

Joy Reese
Nun

Lucy Alpaugh
Nun

Robert D. Raiford
T.V. Announcer

Harry S. Murphy
Reporter #1

Patt Noday
Reporter #2

Robert Lee Edwards
Scapelli Bodyguard

Ronald Lou Edwards
Scapelli Bodyguard

Matthew Zachary Hopkins
Pizza Delivery Boy

Robert Priester
Egon

Preston Lane
James

Jim Asaki
Japanese Businessman #1

Matt Nikko
Japanese Businessman #2

Kevin West
Devo Controller

Jeffrey Pillars
Devo Technician

Frank Welker
Creatures (voice)

Dan Castellaneta
Narrator (voice)

Fred Folger
Goomba (uncredited)

David Kraus
Singing Waiter (uncredited)

Ronnie Jay Leipold
Crazed Lunatic (uncredited)

Alan McCoy
Devo Technician (uncredited)

Mark Jeffrey Miller
Vendor (uncredited)

Carlene Moore
Prostitute (uncredited)

Neil Riddaway
Brooklyn Girl (uncredited)

Joe West
Archaeology Student (uncredited)