Eminem
Jimmy

Kim Basinger
Stephanie

Mekhi Phifer
Future

Brittany Murphy
Alex

Evan Jones
Cheddar Bob

Omar Benson Miller
Sol George

De'Angelo Wilson
DJ IZ

Eugene Byrd
Wink

Taryn Manning
Janeane

Larry Hudson
Bouncer

Proof
Lil'Tic

Mike Bell
Shorty Mike

DJ Head
Battle DJ

Michael Shannon
Greg Buehl

Chloe Greenfield
Lily

Mary Hannigan
Mrs. Helgeland

Anthony Mackie
Papa Doc

Strike
Lyckety-Splyt

Nashawn 'Ox' Breedlove
Lotto

Na'Keya Snoddy
Papa Doc's Girl

Malik Barnhardt
Moochie

Day Golfin
Day

Allen Adams
Omar

Hom
First Parking Lot Rapper

Obie Trice
Second Parking Lot Rapper

Njeri Earth
Third Parking Lot Rapper

Jennifer Kitchen
Willing Girl

Kyla Womack
Alex's Friend

Melissa Zaglanikzny
Christine

Rockey Black
Rocky

Craig Chandler
Paul

Paul Bates
Manny

Miz-Korona
Female Lunch Truck Rapper

Xzibit
Male Lunch Truck Rapper

Abdul Salaam El Razzac
Joe Lee Patton

Steven Monroe
Plant Worker

John Smith Jr.
Lobby Security Guard

Venicia Foreman
WJLB Receptionist

Waverly W. Alford II
Big O

Bushman
WJLB Disc Jockey

Adam Brook
Roy Darucher

Brandon T. Jackson
Chin Tiki Club Goer (uncredited)