Lionel Atwill
Dr. Jerry Xavier

Fay Wray
Joanne Xavier

Lee Tracy
Lee Taylor

Preston Foster
Dr. Wells

John Wray
Dr. Haines

Harry Beresford
Dr. Duke

Arthur Edmund Carewe
Dr. Rowitz

Leila Bennett
Mamie

Robert Warwick
Commissioner Stevens

George Rosener
Otto, Dr. Xavier's Butler

Willard Robertson
Detective O'Halloran

Thomas E. Jackson
Daily World Editor

Harry Holman
Mike, Waterfront Policeman

Mae Busch
Cathouse Madame

Tom Dugan
Sheriff

Raoul Freeman
Morgue Detective (Uncredited)

Selmer Jackson
Willard Keefe, Daily World Night Editor (Uncredited)

Charles McMurphy
Detective at Headquarters (Uncredited)

Ky Robinson
Morgue Detective (Uncredited)

Louise Beavers
Louise (Uncredited)