Johnny Depp
Commander Spencer Armacost

Charlize Theron
Jillian Armacost

Joe Morton
Sherman Reese

Clea DuVall
Nan

Nick Cassavetes
Captain Alex Streck

Donna Murphy
Natalie Streck

Gary Grubbs
NASA Director

Blair Brown
Shelly McLaren

Tom Noonan
Jackson McLaren

Tom O'Brien
Allen Dodge

Lucy Lin
Shelly Carter

Michael Crider
Pat Elliott

Samantha Eggar
Dr. Patraba

Rondi Reed
Dr. Conlin

Conrad Bachmann
Reporter

Sarah Dampf
Paula, 2nd Grade Student

Charles Lanyer
Spencer's Doctor

Gary Carlos Cervantes
Doctor

Seth Barrish
Yuppie Shark

Ellen Lancaster
Dried Up Socialite

Julian Barnes
Waiter

Priscilla Shanks
Woman

Jennifer Burry
Second Woman

Susan Cella
Third Woman

Linda Powell
Fourth Woman

Elston Ridgle
Security Guard

Robert Sella
Maitre D'

Samantha Carpel
Reporter (Video)

Stephen Berger
Doorman

Michael Luceri
Waiter at Party

Ben Van Bergen
Storage Facility Client

Edward Kerr
Pilot

Cole Sprouse
Twin

Dylan Sprouse
Twin

Carl Burrows
Businessman (uncredited)

Buck Holland
Mission Control (uncredited)

Jacob Stein
Calvin, 2nd Grade Student