Alan Cumming
Joe Therrian

Jennifer Jason Leigh
Sally Nash Therrian

John Benjamin Hickey
Jerry Adams

Parker Posey
Judy Adams

Phoebe Cates
Sophia Gold

Kevin Kline
Cal Gold

Owen Kline
Jack Gold

Greta Kline
Evie Gold

Denis O'Hare
Ryan Rose

Mina Badie
Monica Rose

Jane Adams
Clair Forsyth

John C. Reilly
Mac Forsyth

Jennifer Beals
Gina Taylor

Matt Malloy
Sanford Jewison

Mary Lynn Rajskub
Mary-Lynn

Michael Panes
Levi Panes

Gwyneth Paltrow
Skye Davidson

Blair Tefkin
Astrid

Karen Kilgariff
Karen

Molly Bryant
Party Guest

Michael G. Carroll
Party Guest

Craig Chester
Party Guest

Christopher Lawrence
Party Guest

Jessica Queller
Party Guest

JR Reed
Party Guest

Steven Freedman
Yoga Instructor

Norizzela Monterroso
America

Clara Demedrano
Rosa

Sadie Frost
Lucy - Joe's Sister (voice) (uncredited)

Matt McGrath
Jeffrey (uncredited)