John Kassir
Buster Bunny (voice)

Tress MacNeille
Babs Bunny (voice)

Joe Alaskey
Plucky Duck (voice)

Don Messick
Hamton J. Pig / TV Executive (voice)

Cree Summer
Elmyra Duff / Dr. Frankenmyra / Uhura (voice)

Maurice LaMarche
The Brain / Dizzy Devil / Dizzygor / Gossamer / Additional Voices (voice)

Gail Matthius
Shirley the Loon (voice)

Kath Soucie
Fifi La Fume / Little Sneezer (voice) (as Kath Souci)

Danny Cooksey
Montana Max (voice)

Frank Welker
Furrball / Gogo Dodo / Byron Basset / Calamity Coyote / Little Beeper / Gremlin / Additional Voices (voice)

Ron Perlman
Mr. Scratch (voice)

Jim Cummings
Paddy / Villager / Additional Voices (voice)

Jeff Bennett
Shamus / Pumpkin Guy / The World's Biggest Tiny Toon Fan / Additional Voices (voice) (as Jeff Glen Bennett)

June Foray
Witch Hazel (voice)