John Candy
Sheriff Bud B. Boomer

Alan Alda
U.S. President

Rhea Perlman
Deputy Honey

Kevin Pollak
Stuart Smiley, National Security Advisor

Rip Torn
General Dick Panzer

Kevin J. O'Connor
Roy Boy

Bill Nunn
Kabral Jabar

G. D. Spradlin
R.J. Hacker

Jim Belushi
Charles Jackal, NBS Reporter

Steven Wright
RCMP Officer at Headquarters

Brad Sullivan
Gus, CIA Canada Desk Agent

Stanley Anderson
Edwin S. Simon, NBS News Anchor

Richard Council
Russian President Vladimir Krushkin

Wallace Shawn
Canadian Prime Minister Clark MacDonald

Michael Copeman
Panzer's Aide

Beth Amos
Ruthie

Bruce Hunter
President's Aide

Jack Mather
Pops

Kenner Ames
Mountie Sergeant

Roger Dunn
Mountie Major

Natalie Rose
Toronto Kid

Michael Woods
State Trooper #1

Matt Cooke
State Trooper #2

Barbara Schroeder
Newswoman

Tara Meyer
Candy Striper #1

Fab Filippo
Candy Striper #2

Carlton Watson
Clarence Thomason

Stan Coles
Secretary of State

Adrian Hough
Russian Aide

Bryan Armstrong
Auctioneer

Kelsey Binder Moore
Ice Cream Girl #1

Leah Binder Moore
Ice Cream Girl #2

Wally Bolland
Special Ops Soldier

Markus Parilo
Omega Force Leader

Jim Czarnecki
Snake

Tony Proffer
Dell

Ben Hamper
Redneck Guy #1

Michael Moore
Redneck Guy #2

Linda Genovesi
Polite Canadian Woman

Sheila Gray
Hacker Hellstorm (voice)

Dana Brooks
Paulette Kalin

Dan Aykroyd
OPP Officer (uncredited)

Andre Rosey Brown
Man (uncredited)

James Carville
Pentagon Agent for Canadian Intelligence (uncredited)

Michael Dyson
Explosives Tech (uncredited)

Gordon Michael Woolvett
Male Candy Striper (uncredited)