John Cusack
Nick Falzone

Billy Bob Thornton
Russell Bell

Cate Blanchett
Connie Falzone

Angelina Jolie
Mary Bell

Jake Weber
Barry Plotkin

Kurt Fuller
Ed Clabes

Vicki Lewis
Tina Leary

Matt Ross
Ron Hewitt

Jerry Grayson
Leo Morton

Michael Willis
Pat Feeney

Philip Akin
Paul

Mike O'Malley
Pete

Neil Crone
Tom

Matt Gordon
Ken

Joe Pingue
Mark

Shaun Majumder
New Controller

Dwight McFee
Veteran Controller

Rob Smith
Bob

Catherine Lloyd Burns
Tanya Hewitt

Star Jasper
Julie Clabes

Molly Price
Crystal Plotkin

Sarah Knowlton
Beverly

Kiersten Warren
Karen

Andy Dan
Diner Cook

Tennyson Loeh
Diner Waitress

Michael Hyatt
Trudy

Jillian Cameron
Falzone Girl

Michael Cameron
Falzone Boy

Carolyn Scott
Mrs. Connor

Cody Jones
Timmy

Jimmy Ruderman
Scared Student

Paul Brogren
Supermarket Clerk

Gene Dinovi
Enzo Sorrento

Emile Belcourt
Tenor

Robyn Stevan
Sara

Amanda Delaney
Bodybuilder

Ferne Downey
Sorrento Customer

Joe Matheson
Announcer

Gina Clayton
Dynajet Flight Attendant

Matthew Bennett
Dynajet Steward

James Millington
Dynajet Captain

Ramona Milano
TV Reporter

Ray Paisley
K-9 Cop

Rita Tuckett
Lady Sparta

Robert Bidaman
Near Miss Pilot

Dick Callahan
TRACON Guard

Brian King
Honeymoon Man

Julia Paton
Honeymoon Woman

Jenny Parsons
Flight Attendant

John Lefebvre
Pilot

John Robinson
Co-Pilot

Todd Faithfull
Tina's Boyfriend

Richard Bauer
Pilot (voice)

Jim Codrington
Pilot (voice)

William Colgate
Pilot (voice)

Craig Eldridge
Pilot (voice)

Peter Graham
Pilot (voice)

Peter James Howarth
Pilot (voice)

Ray Kahnert
Pilot (voice)

Robert B. Kennedy
Pilot (voice)

Shawn Lawrence
Pilot (voice)

Markus Parilo
Pilot (voice)

Martin Roach
Pilot (voice)

Jonathan Whittaker
Pilot (voice)

Wayne Curnew
Air Traffic Controller (uncredited)

John Carroll Lynch
Doctor Freeze (uncredited)