Nicholas Rowe
Sherlock Holmes

Alan Cox
John Watson

Sophie Ward
Elizabeth Hardy

Anthony Higgins
Professor Rathe

Susan Fleetwood
Mrs. Dribb

Roger Ashton-Griffiths
Det. Sgt. Lestrade

Matthew Ryan
Dudley's Friend

Earl Rhodes
Dudley

Freddie Jones
Chester Cragwitch

Patrick Newell
Bentley Booster

Nadim Sawalha
Khasek - Lower Nile Tavern Owner

Nigel Stock
Rupert T. Waxflatter

Brian Oulton
Master Snelgrove

Donald Eccles
The Reverend Duncan Nesbitt

Matthew Blakstad
Dudley's Friend

Jonathan Lacey
Dudley's Friend

Walter Sparrow
Ethan Engel

Roger Brierley
Mr. Holmes

Vivienne Chandler
Mrs. Holmes

Lockwood West
Curio Shop Owner

John Scott Martin
Cemetery Caretaker

George Malpas
School Porter

Willoughby Goddard
School Reverend

Michael Cule
Policeman with Lestrade

Ralph Tabakin
Policeman in Shop Window

Nancy Nevinson
Hotel Receptionist

Michael Hordern
Older Watson (voice)

Grant Burns
Schoolboy (uncredited)

George Lane Cooper
Acolyte (uncredited)

Salo Gardner
Chestnut Seller (uncredited)

Lew Hooper
Restaurant Patron (uncredited)

Royston Munt
Footman (uncredited)

Henry Roberts
School Master (uncredited)

Fred Wood
Patron (Lower Nile Tavern) (uncredited)