Mel Blanc
Barney Rubble / Dino / Mr. Spacely (voice)

Daws Butler
Elroy Jetson / W.C. Cogswell / Henry Orbit (voice)

Don Messick
Astro / R.U.D.I / Mac / Announcer / Store Manager / Robot (voice)

Henry Corden
Fred Flintstone / Knight (voice)

Jon Bauman
Iggy (voice)

Hamilton Camp
Turk Tarpit (voice)

Julie McWhirter
Betty Rubble / Jet Rivers / Investor / Panelist / Harem Girl (as Julie Dees) (voice)

George O'Hanlon
George Jetson (voice)

Penny Singleton
Jane Jetson (voice)

John Stephenson
Mr. Slate / Moderator / Investor / Poker Player (voice)

Brenda Vaccaro
Didi (voice)

Jean Vander Pyl
Wilma Flintstone / Rosie / Mrs. Spacely (voice)

Janet Waldo
Judy Jetson / Female Computer (voice)

Frank Welker
Dan Rathmoon / Johnny / Mr. Goldbrick (voice)

Patric Zimmerman
(voice)